Glucagon Receptor Rabbit Polyclonal Antibody
Product Specifications
Background
Glucagon receptor (GCGR) Homo sapiens The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM) .[provided by RefSeq, Jan 2010], disease:It is a candidate for certain defects in non-insulin-dependent diabetes mellitus (NIDDM) . The variant in position 40 (Ser) is found in some NIDDM patients, but also in nondiabetic subjects., function:This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system., similarity:Belongs to the G-protein coupled receptor 2 family.
Product Name Alternative
GCGR; Glucagon receptor; GL-R
Gene Name
GCGR
Gene ID
2642
Swiss Prot
P47871
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, ELISA
Field of Research
Neuroactive ligand-receptor interaction
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
54kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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