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CXCR-7 Rabbit Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV) . Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008], caution:Was originally (PubMed:1675791) thought to be the receptor for VIP., function:Receptor for CXCL12/SDF1. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates., online information:CXC chemokine receptors entry, similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Expressed in monocytes, basophils, and B-cells. Lower expression in CD4+ T-lymphocytes and natural killer cells.

Product Name Alternative

CXCR7; CMKOR1; GPR159; RDC1; C-X-C chemokine receptor type 7; CXC-R7; CXCR-7; Chemokine orphan receptor 1; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; RDC-1

Gene Name

CXCR7

Gene ID

57007

Swiss Prot

P25106

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, ELISA

Purification

Affinity purification

Dilution

WB 1:500-1:2000, ICC/IF 1:200-1:1000, ELISA 1:10000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

41kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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