P52 S6 kinase Rabbit Polyclonal Antibody

Catalytic activity:ATP + a protein = ADP + a phosphoprotein., caution:Instead of Lys-820, Arg-820 is found at the binding site., domain:The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site., function:May be involved in transmitting sphingosine-1 phosphate (SPP) -mediated signaling into the cell., similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily., similarity:Contains 1 MIT domain., similarity:Contains 1 PX (phox homology) domain., similarity:Contains 2 protein kinase domains., subcellular location:Also found in some small dot-like or ring-shaped early endosome structures., subunit:Interacts with SPHK1 and phosphatidylinositol 3-phosphate., tissue specificity:Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon., catalytic activity:ATP + a protein = ADP + a phosphoprotein., caution:Instead of Lys-820, Arg-820 is found at the binding site., domain:The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site., function:May be involved in transmitting sphingosine-1 phosphate (SPP) -mediated signaling into the cell., similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily., similarity:Contains 1 MIT domain., similarity:Contains 1 PX (phox homology) domain., similarity:Contains 2 protein kinase domains., subcellular location:Also found in some small dot-like or ring-shaped early endosome structures., subunit:Interacts with SPHK1 and phosphatidylinositol 3-phosphate., tissue specificity:Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.

RPS6KC1; RPK118; Ribosomal protein S6 kinase delta-1; S6K-delta-1; 52 kDa ribosomal protein S6 kinase; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; SPHK1-binding protein