Tensin-2 (phospho Tyr483) Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008], function:Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling., similarity:Contains 1 C2 tensin-type domain., similarity:Contains 1 phorbol-ester/DAG-type zinc finger., similarity:Contains 1 phosphatase tensin-type domain., similarity:Contains 1 SH2 domain., subcellular location:Detected at the end of actin stress fibers., subunit:Interacts with AXL., tissue specificity:Detected in heart, kidney, brain, thymus, spleen, liver, placenta, lung, skeletal muscle and small intestine.
Product Name Alternative
TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2
Gene Name
TENC1
Gene ID
23371
Swiss Prot
Q63HR2
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Phosphorylated
Molecular Weight
152kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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