RXRγ Rabbit Polyclonal Antibody

Retinoid X receptor gamma (RXRG) Homo sapiens This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA) . This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010], caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data., domain:Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain., function:Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA) ., similarity:Belongs to the nuclear hormone receptor family. NR2 subfamily., similarity:Contains 1 nuclear receptor DNA-binding domain.