HSP90β (phospho Ser254) Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012], function:Molecular chaperone. Has ATPase activity., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the heat shock protein 90 family., subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV., subunit:Homodimer. Interacts with TP53/p53 (By similarity) . Interacts with UNC45A. Binding to UNC45A involves 2 UNC45A monomers per HSP90AB1 dimer.
Product Name Alternative
HSP90AB1; HSP90B; HSPC2; HSPCB; Heat shock protein HSP 90-beta; HSP 90; Heat shock 84 kDa; HSP 84; HSP84
Gene Name
HSP90AB1
Gene ID
3326
Swiss Prot
P08238
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
PI3K/Akt; Protein_Acetylation
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Phosphorylated
Molecular Weight
90kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/antibody/APRab04808_Enkilife_EN.pdf
Isotype
IgG
Available Sizes
Curated Selection
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