HDC Rabbit Polyclonal Antibody

This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion, inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010], catalytic activity:L-histidine = histamine + CO (2) ., cofactor:Pyridoxal phosphate., pathway:Amine and polyamine biosynthesis; histamine biosynthesis; histamine from L-histidine: step 1/1., similarity:Belongs to the group II decarboxylase family., subunit:Homodimer.