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P73 Rabbit Monoclonal Antibody

Product Specifications

Background

P73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described.

Product Name Alternative

TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein

Gene Name

P73

Gene ID

7161

Swiss Prot

O15350

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IP

Field of Research

Apoptosis

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IP 1:10-1:20

Form

Liquid

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 70 kDa; Observed MW: 80,70 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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