P21 Rabbit Monoclonal Antibody
Product Specifications
Background
The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.
Product Name Alternative
CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21
Gene Name
P21
Gene ID
1026
Swiss Prot
P38936
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
PI3K-Akt signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:1000
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 18 kDa; Observed MW: 21 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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