Nicastrin Rabbit Monoclonal Antibody

Product Specifications

Background

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) . It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Product Name Alternative

APH2; Ncstn; NCT; Nicastrin

Gene Name

Nicastrin

Gene ID

23385

Swiss Prot

Q92542

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IP

Field of Research

Notch signaling pathway

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IP 1:10-1:20

Form

Liquid

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 78 kDa; Observed MW: 110-120 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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