CRM1 Rabbit Monoclonal Antibody
Product Specifications
Background
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP) . Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
Product Name Alternative
XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog
Gene Name
CRM1
Gene ID
7514
Swiss Prot
O14980
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC 1:50-1:200
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 123 kDa; Observed MW: 123 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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