JMV 167

JMV 167 is antagonist of peripheral cholecystokinin receptor (CKK), with an IC50 of 500 nM[1].

Product Specifications

CAS Number

[120775-49-7]

UNSPSC

12352209

Target

Cholecystokinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/jmv-167.html

Smiles

O=C(NCCC1=CC=CC=C1)[C@H](CC(O)=O)NC([C@H](CCCC)NC([C@H](NC(CNC([C@H](CCCC)NC([C@@H](NC(OC(C)(C)C)=O)CC2=CC=C(C=C2)OS(=O)(O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O

Molecular Formula

C51H68N8O14S

Molecular Weight

1049.20

References & Citations

[1]C Nagain, et al. Synthetic CCK8 analogs with antagonist activity on pancreatic receptors: in vivo study in the rat, compared to non-peptidic antagonists. Pancreas. 1991 May;6 (3) :275-81.