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BACE1 Rabbit Monoclonal Antibody

Product Specifications

Background

Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type.

Product Name Alternative

ASP2; Bace; C76936

Gene Name

BACE1

Gene ID

23821

Swiss Prot

P56818

Host

Rabbit

Reactivity

Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IP

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IP 1:10-1:20

Form

Liquid

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 56 kDa; Observed MW: 70 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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