AMPK alpha Rabbit Monoclonal Antibody
Product Specifications
Background
AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3) . The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia.
Product Name Alternative
PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase
Gene Name
AMPK alpha
Gene ID
5563
Swiss Prot
P54646
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IP
Field of Research
Autophagy, Wnt signaling pathway, PI3K-Akt signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IP 1:10-1:20
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 62 kDa; Observed MW: 62 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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