Phospho-TAK1 (Ser439) Rabbit Monoclonal Antibody
Product Specifications
Background
Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
Product Name Alternative
MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1
Gene Name
Phospho-TAK1 (Ser439)
Gene ID
6885
Swiss Prot
O43318
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC, IP
Field of Research
Apoptosis, TGF-beta signaling pathway, MAPK signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, ICC 1:50-1:200, IP 1:10-1:20
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 67 kDa; Observed MW: 78 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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