Phospho-ERK1/2 (Thr202/Tyr204) / (Thr185/Tyr187) Rabbit Monoclonal Antibody
Product Specifications
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Product Name Alternative
MAPK1/MAPK3
Gene Name
Phospho-ERK1/2 (Thr202/Tyr204) / (Thr185/Tyr187)
Gene ID
5595/5594
Swiss Prot
P27361/P28482
Host
Rabbit
Reactivity
Human, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IP
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IP 1:10-1:20
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 44,42 kDa; Observed MW: 44,42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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