Phospho-IGF1 Receptor (Tyr1166) Rabbit Monoclonal Antibody
Product Specifications
Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Product Name Alternative
IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
Gene Name
Phospho-IGF1 Receptor (Tyr1166)
Gene ID
3480
Swiss Prot
P08069
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IP
Field of Research
PI3K-Akt signaling pathway, Jak-STAT signaling pathway, Hippo signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IP 1:10-1:20
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 155 kDa; Observed MW: 95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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