Phospho-Presenilin 1 (Ser310) Rabbit Monoclonal Antibody
Product Specifications
Background
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) . Requires the other members of the gamma-secretase complex to have a protease activity.
Product Name Alternative
PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182
Gene Name
Phospho-Presenilin 1 (Ser310)
Gene ID
5663
Swiss Prot
P49768
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Apoptosis, Notch signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:1000
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 53 kDa; Observed MW: 22 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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