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Thrombomodulin/CD141 Rabbit Monoclonal Antibody

Product Specifications

Background

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Product Name Alternative

AHUS6; BDCA3; CD141; CD141 antigen; Fetomodulin; Thbd; THPH12; THRM; Thrombomodulin; ; Thrombomodulin

Gene Name

Thrombomodulin/CD141

Swiss Prot

P15306 (mouse) (human:P07204)

Host

Rabbit

Reactivity

Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, FC

Purification

Affinity Purification

Dilution

WB 1:1000-1:2000, IHC 1:100-1:200, FC 1:20-1:100

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 62 kDa ; Observed MW: 105,70 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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