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PIM2 Rabbit Monoclonal Antibody

Product Specifications

Background

Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.

Product Name Alternative

PIM2; Pim2h; ; PIM2

Gene Name

PIM2

Swiss Prot

Q9P1W9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC, IP

Purification

Affinity Purification

Dilution

WB 1:1000-1:2000, ICC 1:50-1:200, IP 1:20-1:50

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 34 kDa ; Observed MW: 37 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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