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TRAP1 Rabbit Monoclonal Antibody

Product Specifications

Background

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Product Name Alternative

HSP75; HSP90L; Trap1; ; Hsp75

Gene Name

TRAP1

Swiss Prot

Q12931

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ICC

Purification

Affinity Purification

Dilution

WB 1:1000-1:2000, IHC 1:100-1:200, ICC/IF 1:50-1:200, ICC 1:50-1:200

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 80 kDa ; Observed MW: 75 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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