GSDMD Rabbit Monoclonal Antibody
Product Specifications
Background
Enables phospholipid binding activity and wide pore channel activity. Involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Acts upstream of or within cellular response to extracellular stimulus. Located in cytosol; extracellular space; and plasma membrane. Part of NLRP3 inflammasome complex. Is expressed in several structures, including gut; liver; lung; metanephros; and spleen. Orthologous to human GSDMD (gasdermin D) . [provided by Alliance of Genome Resources, Apr 2022]
Product Name Alternative
DF5L; M2-4; Dfna5l; GsdmD-1; Gsdmdc1; 1810036L03Rik
Gene Name
GSDMD
Gene ID
69146
Swiss Prot
Q9D8T2
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, FC, IP
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IHC 1:200-1:1000, FC 1:200-1:500, IP 1:20-1:50
Form
Liquid
Buffer
Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Modification
Unmodified
Molecular Weight
Calculated MW:53 kDa; Observed MW:53,31 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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