AMPA Receptor 4 (GluA 4) Rabbit Monoclonal Antibody
Product Specifications
Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) -sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G) . Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]
Product Name Alternative
GLUR4; GLURD; GluA4; GLUR4C
Gene Name
AMPA Receptor 4 (GluA 4) Rabbit Monoclonal Antibody
Gene ID
2893, 14802, 29629
Swiss Prot
P48058, Q9Z2W8, P19493
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, FC
Purification
Affinity Purification
Dilution
WB 1:1000-1:5000, FC 1:10-1:100
Form
Liquid
Buffer
Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Modification
Unmodified
Molecular Weight
Calculated MW:101 kDa; Observed MW:101 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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