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HNF1A Rabbit Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Product Name Alternative

HNF1; LFB1; TCF1; MODY3; TCF-1; HNF-1A; IDDM20

Gene Name

HNF1A

Gene ID

6927, 21405, 24817

Swiss Prot

P20823, P22361, P15257

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:2000, ICC/IF 1:500-1:1000, FC 1:200-1:500

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Unmodified

Molecular Weight

Calculated MW:67 kDa; Observed MW:81 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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