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HDAC6 Rabbit Monoclonal Antibody

Product Specifications

Background

Enables cytoskeletal protein binding activity; protein deacetylase activity; and ubiquitin binding activity. Involved in several processes, including positive regulation of peptidyl-serine phosphorylation; protein deacetylation; and protein destabilization. Acts upstream of or within several processes, including aggresome assembly; cellular protein metabolic process; and neuron projection morphogenesis. Located in several cellular components, including dendrite; microtubule cytoskeleton; and perikaryon. Part of protein-containing complex. Is expressed in several structures, including central nervous system; early embryo; future midbrain; gut gland; and lung. Human ortholog (s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Orthologous to human HDAC6 (histone deacetylase 6) . [provided by Alliance of Genome Resources, Apr 2022]

Product Name Alternative

Hd6; Sfc6; Hdac5; mHDA2

Gene Name

HDAC6

Gene ID

15185

Swiss Prot

Q9Z2V5

Host

Rabbit

Reactivity

Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, FC, IP

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, FC 1:200-1:500, IP 1:20-1:50

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Unmodified

Molecular Weight

Calculated MW:126 kDa; Observed MW:160 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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