Phospho-SIRT1 (Ser47) Rabbit Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Product Name Alternative
SIR2; SIR2L1; SIR2alpha
Gene Name
Phospho-SIRT1 (Ser47) Rabbit Monoclonal Antibody
Gene ID
23411
Swiss Prot
Q96EB6
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IHC 1:200-1:500, ICC/IF 1:100-1:200
Form
Liquid
Buffer
Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Modification
Phosphorylated
Molecular Weight
Calculated MW:82 kDa; Observed MW:120 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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