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Phospho-RNA polymerase II CTD repeat YSPTSPS (Ser2) Rabbit Monoclonal Antibody

Product Specifications

Background

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]

Product Name Alternative

RPB1; RPO2; POLR2; POLRA; RPBh1; RPOL2; NEDHIB; RpIILS; hsRPB1; hRPB220

Gene Name

Phospho-RNA polymerase II CTD repeat YSPTSPS (Ser2) Rabbit Monoclonal Antibody

Gene ID

5430

Swiss Prot

P24928

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC, IP

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:2000, ICC/IF 1:200-1:500, FC 1:200-1:500, IP 1:20-1:50

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Phosphorylated

Molecular Weight

Calculated MW:192 kDa; Observed MW:250 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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