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CD105 Rabbit Monoclonal Antibody

Product Specifications

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Product Name Alternative

END; HHT1; ORW1

Gene Name

CD105

Gene ID

2022

Swiss Prot

P17813

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC

Purification

Affinity Purification

Dilution

WB 1:1000-1:5000, IHC 1:200-1:500

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Unmodified

Molecular Weight

Calculated MW:71 kDa; Observed MW:95 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/recombinant_antibody/AMRe87179_EnkiLife_EN.pdf

Isotype

IgG

Available Sizes

Curated Selection

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