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CD27 Rabbit Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Product Name Alternative

T14; S152; Tp55; TNFRSF7; S152. LPFS2

Gene Name

CD27

Gene ID

939

Swiss Prot

P26842

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:2000, ICC/IF 1:200-1:500, FC 1:100-1:500

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Unmodified

Molecular Weight

Calculated MW:29 kDa; Observed MW:49 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/recombinant_antibody/AMRe87116_EnkiLife_EN.pdf

Isotype

IgG

Available Sizes

Curated Selection

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