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BubR1 Rabbit Monoclonal Antibody

Product Specifications

Background

This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]

Product Name Alternative

MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta

Gene Name

BubR1

Gene ID

701

Swiss Prot

O60566

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:20-1:50

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Unmodified

Molecular Weight

Calculated MW:120 kDa; Observed MW:130 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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