CD8 alpha Rabbit Monoclonal Antibody
Product Specifications
Background
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs) . In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Product Name Alternative
Ly-2; Ly-B; Ly-35; Lyt-2; BB154331
Gene Name
CD8 alpha
Gene ID
12525
Swiss Prot
P01731
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, FC, IP
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IHC 1:200-1:2000, FC 1:200-1:500, IP 1:20-1:50
Form
Liquid
Buffer
Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Modification
Unmodified
Molecular Weight
Calculated MW:28 kDa; Observed MW:35-42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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