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RUNX3 Rabbit Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Product Name Alternative

AML2; CBFA3; PEBP2aC

Gene Name

RUNX3

Gene ID

864

Swiss Prot

Q13761

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, IP

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:500-1:2000, IP 1:20-1:50

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Unmodified

Molecular Weight

Calculated MW:44,46 kDa; Observed MW:44,46 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/recombinant_antibody/AMRe86839_EnkiLife_EN.pdf

Isotype

IgG

Available Sizes

Curated Selection

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