Galectin-9 Rabbit Monoclonal Antibody
Product Specifications
Background
Binds galactosides (By similarity) . Has high affinity for the Forssman pentasaccharide (By similarity) . Ligand for HAVCR2/TIM3 (By similarity) . Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (By similarity) . Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth (PubMed:20937702) . Ligand for P4HB; the interaction retains P4HB at the cell surface of Th2 T-helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307) . Ligand for CD44; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (PubMed:25065622) .
Product Name Alternative
Gal-9; Lgals5; LGALS35; AA407335; AI194909; AI265545; galectin-9
Gene Name
Galectin-9
Gene ID
16859
Swiss Prot
O08573
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB
Purification
Affinity Purification
Dilution
WB 1:500-1:2000
Form
Liquid
Buffer
Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Modification
Unmodified
Molecular Weight
Calculated MW:40 kDa; Observed MW:40 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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