PKR Rabbit Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Product Name Alternative
PKR; PRKR; EIF2AK1; PPP1R83
Gene Name
PKR
Gene ID
5610
Swiss Prot
P19525
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, FC, IP
Purification
Affinity Purification
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200, ICC/IF 1:20-1:50, FC 1:20-1:50, IP 1:20-1:100
Form
Liquid
Buffer
Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Modification
Unmodified
Molecular Weight
Calculated MW:62 kDa; Observed MW:74 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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