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DKK1 Rabbit Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017]

Product Name Alternative

SK; DKK-1

Gene Name

DKK1

Gene ID

22943

Swiss Prot

O94907

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC

Purification

Affinity Purification

Dilution

WB 1:1000-1:5000, IHC 1:200-1:1000

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Unmodified

Molecular Weight

Calculated MW:29 kDa; Observed MW:28-40 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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