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Metabotropic Glutamate Receptor 5 Rabbit Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Product Name Alternative

MGlu5; GPRC1E; MGLUR5; PPP1R86

Gene Name

Metabotropic Glutamate Receptor 5

Gene ID

2915

Swiss Prot

P41594

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, FC

Purification

Affinity Purification

Dilution

WB 1:1000-1:5000, IHC 1:200-1:500, FC 1:10-1:100

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Unmodified

Molecular Weight

Calculated MW:132 kDa; Observed MW:150,300 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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