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MYBPC3 Rabbit Monoclonal Antibody

Product Specifications

Background

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

Product Name Alternative

FHC; CMH4; CMD1MM; LVNC10; MYBP-C

Gene Name

MYBPC3

Gene ID

4607

Swiss Prot

Q14896

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB

Purification

Affinity Purification

Dilution

WB 1:1000-1:5000

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Unmodified

Molecular Weight

Calculated MW:141 kDa; Observed MW:150 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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