MYBPC3 Rabbit Monoclonal Antibody
Product Specifications
Background
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
Product Name Alternative
FHC; CMH4; CMD1MM; LVNC10; MYBP-C
Gene Name
MYBPC3
Gene ID
4607
Swiss Prot
Q14896
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB
Purification
Affinity Purification
Dilution
WB 1:1000-1:5000
Form
Liquid
Buffer
Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Modification
Unmodified
Molecular Weight
Calculated MW:141 kDa; Observed MW:150 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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