Cripto1 Rabbit Monoclonal Antibody
Product Specifications
Background
GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714) . Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953) .2 Publications GO - Molecular functioni
Product Name Alternative
V1S4; TCRGV4
Gene Name
Cripto1
Gene ID
6977
Swiss Prot
P13385
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IP
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IP 1:20-1:50
Form
Liquid
Buffer
Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Modification
Unmodified
Molecular Weight
Calculated MW:21 kDa; Observed MW:18, 20 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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