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MtTFA Rabbit Monoclonal Antibody

Product Specifications

Background

Enables mitochondrial promoter sequence-specific DNA binding activity. Involved in mitochondrial transcription. Acts upstream of or within mitochondrial respiratory chain complex assembly. Located in mitochondrial nucleoid. Is active in mitochondrion. Is expressed in several structures, including brain; branchial arch; genitourinary system; limb; and pancreas. Used to study Kearns-Sayre syndrome and Parkinson's disease. Human ortholog (s) of this gene implicated in Alzheimer's disease; Huntington's disease; Parkinson's disease; amyotrophic lateral sclerosis; and mitochondrial DNA depletion syndrome 15. Orthologous to human TFAM (transcription factor A, mitochondrial) . [provided by Alliance of Genome Resources, Jun 2025]

Product Name Alternative

Hmgts; mtTFA; tsHMG; TFAM; Transcription factor A, mitochondrial

Gene Name

MtTFA

Gene ID

2178083474

Swiss Prot

P40630, Q91ZW1

Host

Rabbit

Reactivity

Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, FC, IP

Purification

Affinity Purification

Dilution

WB 1:1000-1:5000, ICC/IF 1:200-1:500, FC 1:200-1:500, IP 1:20-1:50

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Unmodified

Molecular Weight

Calculated MW:28 kDa; Observed MW:24 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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