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Phospho-YAP1 (Ser127) Rabbit Monoclonal Antibody

Product Specifications

Background

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

Product Name Alternative

YAP; YKI; COB1; YAP2; YAP65

Gene Name

Phospho-YAP1 (Ser127)

Gene ID

10413

Swiss Prot

P46937

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC

Purification

Affinity Purification

Dilution

WB 1:2000-1:20000, IHC 1:100-1:200

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Modification

Phosphorylated

Molecular Weight

Calculated MW:55 kDa; Observed MW:70-75 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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