JAB1 Rabbit Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
Product Name Alternative
CSN5; JAB1; SGN5; MOV-34
Gene Name
JAB1
Gene ID
10987
Swiss Prot
Q92905
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB
Purification
Affinity Purification
Dilution
WB 1:1000-1:5000
Form
Liquid
Buffer
Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Modification
Unmodified
Molecular Weight
Calculated MW:38 kDa; Observed MW:38 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC204264L3V 200 µL
MFSD2A (NM_032793) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
orb3053909-01 20 µg
Recombinant Human Thioredoxin reductase 1, cytoplasmic (TXNRD1), partial
Sign In for Pricing
View Details orb3053909-02 100 µg
Recombinant Human Thioredoxin reductase 1, cytoplasmic (TXNRD1), partial
Sign In for Pricing
View Details