DNAJB6 Rabbit Monoclonal Antibody
Product Specifications
Background
Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
Product Name Alternative
DJ4; MRJ; DnaJ; HSJ2; HHDJ1; HSJ-2; MSJ-1; LGMD1D; LGMD1E
Gene Name
DNAJB6
Gene ID
10049
Swiss Prot
O75190
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 36 kDa; Observed MW: 36 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1478613-01 0.02 mg (E-Coli)
Recombinant Bovine SPRY domain-containing SOCS box protein 3 (SPSB3)
Sign In for Pricing
View Details MBS1478613-02 0.02 mg (Yeast)
Recombinant Bovine SPRY domain-containing SOCS box protein 3 (SPSB3)
Sign In for Pricing
View Details MBS1478613-03 0.1 mg (E-Coli)
Recombinant Bovine SPRY domain-containing SOCS box protein 3 (SPSB3)
Sign In for Pricing
View Details MBS1478613-04 0.1 mg (Yeast)
Recombinant Bovine SPRY domain-containing SOCS box protein 3 (SPSB3)
Sign In for Pricing
View Details MBS1478613-05 0.02 mg (Baculovirus)
Recombinant Bovine SPRY domain-containing SOCS box protein 3 (SPSB3)
Sign In for Pricing
View Details MBS1478613-06 0.02 mg (Mammalian-Cell)
Recombinant Bovine SPRY domain-containing SOCS box protein 3 (SPSB3)
Sign In for Pricing
View Details