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CDKN2A/p16INK4a Rabbit Monoclonal Antibody

Product Specifications

Background

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.CautionThe proteins described here are encoded by the gene CDKN2A, but are completely unrelated in terms of sequence and function to tumor suppressor ARF (AC Q64364) which is encoded by the same gene.

Product Name Alternative

Cdkn2a; P16ink4a; Cyclin-dependent kinase 4 inhibitor A (CDK4I) ; p16-INK4a ; p16-INK4

Gene Name

CDKN2A/p16INK4a

Gene ID

12578

Swiss Prot

P51480

Host

Rabbit

Reactivity

Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC, IP

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, ICC 1:50-1:200, IP 1:10-1:20

Form

Liquid

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 18 kDa; Observed MW: 18 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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