BRAT1 Rabbit Monoclonal Antibody
Product Specifications
Background
Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523) . Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371) . Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994) .
Product Name Alternative
BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1
Gene Name
BRAT1
Gene ID
221927
Swiss Prot
Q6PJG6
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC, IP
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, ICC 1:50-1:200, IP 1:10-1:20
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 88 kDa; Observed MW: 88 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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