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Argonaute 2 Rabbit Monoclonal Antibody

Product Specifications

Background

Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC) . Can also upregulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and upregulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.

Product Name Alternative

Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD

Gene Name

Argonaute 2

Gene ID

27161

Swiss Prot

Q9UKV8

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC, IP

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, ICC 1:50-1:200, IP 1:10-1:20

Form

Liquid

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 97 kDa; Observed MW: 97 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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