Alpha Synuclein Rabbit Monoclonal Antibody
Product Specifications
Background
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies) .
Product Name Alternative
SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP
Gene Name
Alpha Synuclein
Gene ID
6622
Swiss Prot
P37840
Host
Rabbit
Reactivity
Human, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, IP
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, IP 1:10-1:20
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 14 kDa; Observed MW: 18 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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