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Alpha Synuclein Rabbit Monoclonal Antibody

Product Specifications

Background

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies) .

Product Name Alternative

SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP

Gene Name

Alpha Synuclein

Gene ID

6622

Swiss Prot

P37840

Host

Rabbit

Reactivity

Human, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, IP

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IHC 1:50-1:100, IP 1:10-1:20

Form

Liquid

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 14 kDa; Observed MW: 18 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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