Phospho-Amyloid Precursor Protein (Thr743) Rabbit Monoclonal Antibody
Product Specifications
Background
APP a cell surface receptor that influences neurite growth, neuronal adhesion and axonogenesis. Cleaved by secretases to form a number of peptides, some of which bind to the acetyltransferase complex Fe65/TIP60 to promote transcriptional activation.
Product Name Alternative
APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II
Gene Name
Phospho-Amyloid Precursor Protein (Thr743)
Gene ID
351
Swiss Prot
P05067
Host
Rabbit
Reactivity
Human, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC, IP
Field of Research
Apoptosis, Notch signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, ICC 1:50-1:200, IP 1:10-1:20
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 87 kDa; Observed MW: 100 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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