Hsp27 Rabbit Monoclonal Antibody
Product Specifications
Background
Heat shock protein (HSP) 27 is one of the small HSPs that are constitutively expressed at different levels in various cell types and tissues. Like other small HSPs, HSP27 is regulated at both the transcriptional and posttranslational levels. In response to stress, the HSP27 expression increases several-fold to confer cellular resistance to the adverse environmental change. HSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway.
Product Name Alternative
HSPB1; HSP27; HSP28; Heat shock protein beta-1; HspB1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27
Gene Name
Hsp27
Gene ID
3315
Swiss Prot
P04792
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC, IP
Field of Research
MAPK signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC 1:50-1:200, IP 1:10-1:20
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 23 kDa; Observed MW: 27 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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